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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcb51025b6ccd069b0a5d738ed3d5e46c7641f4c81ee62a30996328818225178' 
  AND token = 'jEHGKmlrbSYJGbyGSOnuoGfEhnOxkKHe2V0gZtu/HEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}