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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed3d6211c08159fd158b6f11755eaae6aa8e8c4e7960b4da1ea0a1239b733395' 
  AND token = 'hQrwe3v9ZQ5MY++p4H2iXEjH/dJNYjKh3nZ9b91NPFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}