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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85abe258014eeb6e3d7a6073322a5e16e722f36e81442ac8ad8e018722fb52b9' 
  AND token = '/arTB4+U8OZMmOJhHSVBNMR0o7SENPuLRJwzz/qDd10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}