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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6012dd4e3c4d63355e2ac8a3c75d9f2b4266a422f8205f2e81712f4aad60002c' 
  AND token = 'c8Yk6tbKlmPqrN+BQRVLCd17OGQtyypBgcltKGQxEFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}