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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b250c7bf41ecf2de8d03e1c8090f6163bfe35b8b418b2e620b48b8da0d007828' 
  AND token = '/7sm8r6SF0k4Hkww95IYMXIHwFQsjhzLoCRtWbvBEcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}