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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac527186bcff9d4630d1fe0b9c00de623cb0b28316723b0137a0d0d72b220e40' 
  AND token = 'uZApRnpOyvl5D7kDe5mVTXh2uci/n8ZDl5ePMYwHLHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}