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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3ef998ab53a12e626ca5c2e5a32daa8139e1145154af9fb84a2a7ac999c7112' 
  AND token = 'w0RxpkQhvZedGGKh2uDNYFiWyx1JkJFvoGWoshnkg2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}