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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aed9f9ceed622b3810e4299ffdb67eec621f869450aba3c03c441a090da22108' 
  AND token = 'XvS5GzdOnezrK48INr7+zPyyqVfHyKE/BbMODURM8kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}