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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '193c22afc72dadc7015f473c3fe36f1c5daed248077f2b8b8e373cfe0f8f3f22' 
  AND token = 'OGlcJw8nTN08ZCQfDFbhVLYfAiLz4lPWiha3fPlsCxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}