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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5022a16be77271e2f6ae2c50543f761a74897e608fad4f6c117a0d646e76fea4' 
  AND token = 'D3ZlyOWgAdcjNwdp+gJLTB+kYdZuleexnV0rAFTfyDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}