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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f57217dfd9b60bd70f5a6eef53b65e5216e48ddb00ed9b57f7cab7413a9924' 
  AND token = 'kG5HpeOJ5jydSwU9j781cvQnA2kG0ghJmeL25nNmzD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}