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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216602dbd21ffa618699445ca8da4d8a791d659cbe17dfc01a8cc1519cfc57e2' 
  AND token = 'D6AYKJz42l8sfgLCF7xJyTGMsZUp0FDOU1jF4gdTPxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}