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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3044916252a51735f09766a926d3595f4039491e076cbcef379a7565f2a1ae9' 
  AND token = 'HxPQL/FjW2C0tEL+xyvu4BhapyXQwf3BnCbWTLQX5z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}