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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e423655081b59b643e82f80c0dc575525353c28b796f49636a1c83792f50fbf0' 
  AND token = 'Oul/576JQ+7pH9WQd7+zxt2DxwrCqyV9hevIyMEauaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}