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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e82b61304f3e0e24dfd848abf4a2f53980ab2d7c64b7222ddc9024406c783a7d' 
  AND token = 'nsbooN5xuAxr/AfB08uRRpFCw/hC5e7fu61q6nAgu0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}