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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '067b3abd4493798c83e988a7d11909722806107105012c6337a73310c6f53419' 
  AND token = 'ur+UUeRdktnZo7DHS6XE3Dgvo+Kmd4HGUFVm4DoC2WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}