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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea602c294f54fdfcce5d1a69c498e18db3980e38f2094ce20fc4b00ddac6b2e7' 
  AND token = 'W2WSYfSydp4MtCKCZmA2GoJgZ1uGFQc59p6AgbXhADM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}