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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cfed23673f08f4fd0c51c06c80c94c7e1c42dd59259775a1cc15e91e10dde8b' 
  AND token = '9Nv27vLJ1JMWFa9h5mgyHaPAll7aJV9pO2So2S2TfU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}