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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff69fe77e06bbc3fc4d8a590469cab04ae24c2263eac7e4cb2c353ea280e4678' 
  AND token = 'DFoPc56ajEfu3nzTJ+Krp//d31H0uAtjSnVbuHwHqIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}