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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9537e64a2b8e801fbd15ba39f0c3aebf11b11c9493aada7fd52c324b4f827b' 
  AND token = 'MCNOP6VMV1Z4pi5MgRfXb/3ksYhVi1RGEQzBwG6lFAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}