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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b049853250c783f0ca9e5e3f3ec97ace8c84dafb5971726bc7a5460d5908c84' 
  AND token = 'tKmzmf8AbD0Tn1N6eEVboHdqxvtldWHYffbcD20TmLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}