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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4f970d1e464c7636a18586f40b98a19f63203488de58c6eb65e54cd1616d22' 
  AND token = 'XOyd/jawcqs0NqDsIBCLLu1R3t4aH6VfXk18YQHX2hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}