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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cfeb30afb1534194a56149d5771a4791ed2f2139a051ba83ec74d9bed2922f3' 
  AND token = 'dPlXdZHuVsSSR4gA1yivlJ1AoVtU3uGnFr47PR5FuyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}