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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b89ce04cdd2b1a447ad1880a210b436d02efa56e9462dbe2e5b0b3be650e901' 
  AND token = 'nOjr2I1JunYGUwCC+TNTD2tU15WUoOPtp2tB3PWLdEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}