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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c97cb34878ddcc3578b38089c2fb0beb29553fec6c488210c92d791992c0fc45' 
  AND token = 'sMB2KYdBnpHWjg0mGsWXO7R9V5ArQb7KUYAuSMHfHW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}