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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee7cd3e9dcc3a2a3c9840d7691549d9ec274d025ee765c861ee576163d95d246' 
  AND token = 'QvTsUTpotDlHv7R/BzbXCNqXrxU7jwpFlyv24hBY4Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}