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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5cd37850e71d20eb61126c8c8a7cde5eadda6c684ee7fcc6fadccc143a614b' 
  AND token = 'Nw5hqO5JCTL2x/joX8/vO9dMs+CxDouqKCPFI5pmfrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}