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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '573567f3a4861c0b5ee711c7fa34810a7ff1e9372a4021c70ca7e5faefc04402' 
  AND token = 'oaDIkI8rpJl/h8+wdblSzylIxaZkA2hAF8awIHf5jOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}