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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306479b05f60ba4487e13c5de349debac32a034fd640e05ae60ae99ac364742a' 
  AND token = 'A1vVwy6R1jPFbmwSdiALArM0e4KhRsehUPIW3NdUcdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}