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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c089629bf9a7a5134950e7962118840b07fcd8ce872308f32a2845117832f09c' 
  AND token = 'TI2+Bd8nNJcJSA0jaGDUR8G0IUuhg7+jTYrR0hkL9aA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}