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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1008a5bba5191c8cf5a78e7fb51f4956369574ad73a4ea50b22142a8e380a261' 
  AND token = 'KDikb2nqm1Pnn1peWP8vpHBEBEuVSUfsC4hr52BB+30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}