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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f8cd3468b80eb833f2446ca40d8f53910857b80be2bc20dec7b5174003357b' 
  AND token = 'Na+bKPUG5bpF5Q72AquZ+zVAWjQBcA3+s6H80T74pIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}