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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1ecf37282119dff6499562886ace1c2e3b45a23db49e601e7bcfdc7aab8df64' 
  AND token = 'aPNpkVaFrOnSG6+vRbMLLIidJLD7cFAwjrRKEEMP050=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}