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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8afd9b692f8c35200707fd8976da9f13024790df6e7d5c8027dfcb11cbfcb295' 
  AND token = 'k7EYRwT0iWVZSbixl8KvoOC/v8VNiLk39cUFnRFgNng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}