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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7438b131f8449ef574ea5edaf98ab81d077ea13f0af1fcbd0dc6b8aee6673fb' 
  AND token = 'U5xwrAll6k0i9vkhTMnzF//UdzfVyytu2wMsM1nAjt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}