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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37c6cc53c3096f93b2be09d7bc54683fa0c583d60e7cd16ffbb762c971075c8d' 
  AND token = 'yHGkPpVET9t/bKaTtDBMo60mISM10SU8Mc0rGq61CJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}