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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91b45ee16d03693ea7f3d79d8dfbafffbe31777d872987481d1a88af54cde17c' 
  AND token = 'yBDzTjL9I09eNnB4DR8gDZS1bixjFW1sjF4qt4pcneI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}