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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46c34d4a75989eb2ab54e853209d54460f9741db19594db6f8ab557660ef5f9' 
  AND token = 'x4Al+yHaT3eE8Y6Uginsb2KjT0e9MXYSr8rH72UpV74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}