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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e9971d99a33bc3c1994f5ba05fb7108ec15c4386d17cf86e301564982e45634' 
  AND token = 'EziBN4Ejnp6QE4wEFR9BAnnzWYflyOrMM6Id0LggDJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}