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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16c97ddd8c4f8bf570645aaf87448c5ab9a6d721af0aa99c96b8eb2e7b177b8' 
  AND token = 'BpZx0br8YVzLdySWKEFwam00txsQzNcbWENprpEc/8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}