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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e25cd2aecda75db0c1f0cc40eada9c05251a389e75d33d5f5b1c08ff93e1f5d' 
  AND token = 'lMAqYYKPEbw4tx+vQStgAKt8AqFDXcz0DoBQaqQl1hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}