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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4366e7ebb4d77449385dff889dd1afda92303d415dd0d882bbd4d402606d5ba0' 
  AND token = 'X2b7JCnhQLb+uIxnds/t/i5BCbgkYuQy0bGSEfE5xeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}