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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe254a80f184c222b298c702fd1fac92beafbd6672de7695ae21bc9090b9d2f7' 
  AND token = 'yEQ02kCn8NbdjSeUSfBIFJkNmAP7NzMKzGycNaDlf/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}