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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c47a8926c739e8fd6f652cf71c552ad8af63d2eabb6d96359c40504e5407ab0' 
  AND token = 'EkxfX9bdXdEZoV62yxQ27tMKS6bTmv9QXt1mNDCw3IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}