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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a81f449d917bdb1add3a6a991d17359efbfa9d3f9039791c1f474cd46734431' 
  AND token = '39FPtBKq/bGBcAFoZ0TAFitC4QC3/iJhBT4qGTQ2Bj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}