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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86a03ced95f9e16f336a02afff29d656a296c69ed95e3a5f25351cbe0bdc7035' 
  AND token = 'VEtf9zXtTSMFVS/V7WxDbaDpyCTpShJh/u/ZhsOPQx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}