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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf52a6d8511b0b9fdd3f12b3a5af0c96f2e64a38fc29b3a652d23aa2d0535590' 
  AND token = 'i3/NQCMQF49UieAX266wwJKVkoJ5jWo/2mqHB9v+luo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}