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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a11a21fae9d6d5f4b208d1db5aed3d987d10e40fbf18d7ec732232ff9a582284' 
  AND token = '+870LzX0H7WRzoCFS6ZeuZX/dQbt5sJQ+/u3wkGlOrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}