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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3ad6454e41845d643be0a6010ae220b59d04b8fc056684c4a17d2e29527e4e1' 
  AND token = 'PkH2W/H7ZXOLKZsiSSjK0WcxAhrGUyGyML54tJ//aDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}