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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a35e8b747a0e2ec05aa3b63aa9b879394405573f1a10ae4c899345d11b6e23b8' 
  AND token = '2Vx8CQXwCi/uCYgTLC+tg7I5WRDkHFCiH1DgaPwQioI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}